Tetrahedron letters

Preparation of enantiomerically enriched α-hydroxystannanes via enzymatic resolution

JM Chong, EK Mar

Index: Chong, J. Michael; Mar, Eduardo K. Tetrahedron Letters, 1991 , vol. 32, # 41 p. 5683 - 5686

Full Text: HTML

Citation Number: 30

Abstract

Abstract The porcine pancreatic lipase (PPL) catalyzed esterifications of α- hydroxystannanes RCH (OH) SnMe 3 (R= Me, Et) and MeCH (OH) SnEt 3 with 2, 2, 2- trifluoroethyl valerate afford good yields and excellent enantiomeric (> 95% ee) purities of