2, 4??and 2, 5??Disubstituted Arylthiazoles: Rapid Synthesis by C–H Coupling and Biological Evaluation

…, TN Uehara, S Tani, J Yamaguchi…

Index: Lohrey, Lilia; Uehara, Takahiro N.; Tani, Satoshi; Yamaguchi, Junichiro; Humpf, Hans-Ulrich; Itami, Kenichiro European Journal of Organic Chemistry, 2014 , vol. 2014, # 16 p. 3387 - 3394

Full Text: HTML

Citation Number: 3

Abstract

Abstract Life-threatening infections caused by bacteria that have developed resistance to common antibiotics, such as methicillin-resistant Staphylococcus aureus (MRSA), have become a serious problem in hospitals and other areas all over the world. Thus, the development of an effective class of antibiotics against these bacteria is an urgent subject. Herein, we report a step-economical and diversity-oriented synthesis of a series of 2- ...