Structural similarity and its surprises: endothelin receptor antagonists-process research and development report

R Jansen, M Knopp, W Amberg…

Index: Organic Process Research and Development, , vol. 5, # 1 p. 16 - 22

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Citation Number: 29

Abstract

... Organic Process Research & ... Nevertheless, both processes were subjected to pilot plant scale testing. In both cases comparable yields were obtained. ... This procedure was used in the first pilot plant process and rapidly produced 14 kg of BSF 302146 (14% overall yield). figure ...