Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate

Modify Date: 2024-01-12 10:47:12

Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate Structure
Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate structure
Common Name Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate
CAS Number 177036-78-1 Molecular Weight 286.322
Density 1.2±0.1 g/cm3 Boiling Point 440.7±40.0 °C at 760 mmHg
Molecular Formula C17H18O4 Melting Point N/A
MSDS N/A Flash Point 159.4±20.8 °C

 Names

Name (S)-2-hydroxy methyl 3-methoxy-3,3-diphenylpropionate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 440.7±40.0 °C at 760 mmHg
Molecular Formula C17H18O4
Molecular Weight 286.322
Flash Point 159.4±20.8 °C
Exact Mass 286.120514
PSA 55.76000
LogP 3.99
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.560

 Safety Information

HS Code 2918990090

 Synthetic Route

~98%

Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate Structure

Methyl 2-hydrox...

CAS#:177036-78-1

Literature: CIPLA LIMITED; KING, Lawrence; RAO, Dharmaraj Ramachandra; KANKAN, Rajendra Narayanrao; NAIK, Sanjay; GHAGARE, Maruti; CHIKHALIKAR, Sandip Vasant Patent: WO2013/57468 A1, 2013 ; Location in patent: Page/Page column 25 ;

~95%

Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate Structure

Methyl 2-hydrox...

CAS#:177036-78-1

Literature: CIPLA LIMITED; KING, Lawrence; RAO, Dharmaraj Ramachandra; KANKAN, Rajendra Narayanrao; NAIK, Sanjay; GHAGARE, Maruti; CHIKHALIKAR, Sandip Vasant Patent: WO2013/57468 A1, 2013 ; Location in patent: Page/Page column 20-21 ;

~%

Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate Structure

Methyl 2-hydrox...

CAS#:177036-78-1

Literature: Journal of Medicinal Chemistry, , vol. 42, # 16 p. 3026 - 3032

~%

Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate Structure

Methyl 2-hydrox...

CAS#:177036-78-1

Literature: Organic Process Research and Development, , vol. 5, # 1 p. 16 - 22

~%

Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate Structure

Methyl 2-hydrox...

CAS#:177036-78-1

Literature: WO2010/70658 A2, ; Page/Page column 20 ; WO 2010/070658 A2

~%

Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate Structure

Methyl 2-hydrox...

CAS#:177036-78-1

Literature: US2011/263854 A1, ; US 20110263854 A1

~%

Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate Structure

Methyl 2-hydrox...

CAS#:177036-78-1

Literature: US2011/263854 A1, ; US 20110263854 A1

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate
(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
Benzenepropanoic acid, α-hydroxy-β-methoxy-β-phenyl-, methyl ester, (αS)-
(S)-2-hydroxy-3-methoxy-3,3-diphenylpropanoic acid methyl ester
Benzenepropanoic acid, α-hydroxy-β-methoxy-β-phenyl-, methyl ester
Methyl (2S)-2-hydroxy-3-methoxy-3,3-diphenylpropanoate