Organic letters

Transition-Metal-Free Sonogashira-Type Cross-Coupling of Alkynes with Fluoroarenes

G Jin, X Zhang, S Cao

Index: Zhang, Jian; Wu, Jingjing; Xiong, Yang; Cao, Song Chemical Communications, 2012 , vol. 48, # 68 p. 8553 - 8555

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Citation Number: 22

Abstract

A novel, inexpensive, and efficient palladium-, copper-, ligand-, and amine-free Sonogashira- type cross-coupling reaction of terminal alkynes with unreactive aryl fluorides in the presence of sodium, sodium methoxide, and calcium hydroxide under the assistance of a