Tetrahedron letters

Chemoselective three-component coupling via a tandem Pd-catalyzed boron-Heck and Suzuki reactions

J O'Neill, KS Yoo, KW Jung

Index: O'Neill, Justin; Yoo, Kyung Soo; Jung, Kyung Woon Tetrahedron Letters, 2008 , vol. 49, # 51 p. 7307 - 7310

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Citation Number: 7

Abstract

A new approach is herein reported to prepare biaryl derivatives via a tandem Pd-catalyzed boron-Heck and Suzuki reactions. This one-pot tandem process avoided purification or addition of extra catalyst between steps. The resulting biaryl compounds can be prepared with substrate variability in good to moderate yields.