Tetrahedron

Three component synthesis of β-amino carbonyl compounds using indium trichloride-catalyzed one-pot Mannich-type reaction in water

TP Loh, SBKW Liung, KL Tan, LL Wei

Index: Loh, Teck-Peng; Liung, Sarah B. K. W.; Tan, Kee-Leng; Wei, Lin-Li Tetrahedron, 2000 , vol. 56, # 20 p. 3227 - 3237

Full Text: HTML

Citation Number: 160

Abstract

The use of indium trichloride as catalyst in a one-pot Mannich reaction in water gives high yields for the formation of β-aminoketones/esters/acids is described. The catalyst can be recycled when the reaction is complete (Loh T.-P.; Wei L.-L. Tetrahedron Lett. 1998, 39, 323).