3-(4-Piperidinyl)-and 3-(8-aza-bicyclo [3.2. 1] oct-3-yl)-2-phenyl-1H-indoles as bioavailable h5-HT 2A antagonists

J Crawforth, S Goodacre, R Maxey, S Bourrain…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 24 p. 2701 - 2703

Full Text: HTML

Citation Number: 13

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... In this letter, we describe the synthesis and receptor binding affinities of compounds where the tryptamine side chain has been constrained within a ring. ...

3-(4-Piperidinyl)-and 3-(8-aza-bicyclo [3.2. 1] oct-3-yl)-2-...

[Crawforth, James; Goodacre, Simon; Maxey, Robert; Bourrain, Sylvie; Patel, Smita; Marwood, Rosemarie; O'Connor, Desmond; Herbert, Richard; Hutson, Peter; Rowley, Michael Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 24 p. 2701 - 2703]