The Journal of Organic Chemistry

The synthesis of heterobifunctional linkers for the conjugation of ligands to molecular probes

CR Bertozzi, MD Bednarski

Index: Bertozzi, Carolyn R.; Bednarski, Mark D. Journal of Organic Chemistry, 1991 , vol. 56, # 13 p. 4326 - 4329

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Citation Number: 82

Abstract

The availability of bifunctional water-soluble compounds with flexible dimensions is important for the conjugation of small molecules to proteins or molecular probe^.^^'These bifunctional molecules can be used in antibody production, drug delivery, protein immobilization, and for the study of enzymea and receptor^.^ Polyethylene glycol (1) office of Naval Ressarch predoctoral fellow; AT&T Bell Labora-tories GRPW awardee.