Tetrahedron

Electrochemical generation of N-(2, 2-dichlorovinyl) amides

A Guirado, R Andreu, A Cerezo, J Gálvez

Index: Guirado, Antonio; Andreu, Raquel; Cerezo, Alfredo; Galvez, Jesus Tetrahedron, 2001 , vol. 57, # 23 p. 4925 - 4931

Full Text: HTML

Citation Number: 13

Abstract

A convenient method for the synthesis of N-(2, 2-dichlorovinyl) amides has been established. Treatment of chloralamides with phosphorus pentachloride provides N-(1, 2, 2, 2-tetrachloroethyl) amides in high yields whose electrochemical reduction leads to the title compounds in fair to quantitative yields. This approach exhibits superior efficiency and versatility than previously reported procedures.

 Related Synthetic Route

~90%

Learn More

~%

Learn More

~98%

Learn More

~%

Learn More

~89%

Learn More

~87%

Learn More

~%

Learn More

~92%

Learn More

~94%

Learn More

~%

Learn More

~77%

Learn More

~89%

Learn More

~%

Learn More

~70%

Learn More

~%

Learn More

~93%

Learn More

~91%

Learn More

~%

Learn More

~95%

Learn More

~73%

Learn More

~%

Learn More