4-Nitrobenzamide

Modify Date: 2025-08-21 18:25:50

4-Nitrobenzamide Structure
4-Nitrobenzamide structure
Common Name 4-Nitrobenzamide
CAS Number 619-80-7 Molecular Weight 166.134
Density 1.4±0.1 g/cm3 Boiling Point 368.0±25.0 °C at 760 mmHg
Molecular Formula C7H6N2O3 Melting Point 199-201 °C(lit.)
MSDS Chinese USA Flash Point 176.3±23.2 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4-Nitrobenzamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 368.0±25.0 °C at 760 mmHg
Melting Point 199-201 °C(lit.)
Molecular Formula C7H6N2O3
Molecular Weight 166.134
Flash Point 176.3±23.2 °C
Exact Mass 166.037842
PSA 88.91000
LogP 0.82
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.612
Stability Stable. Incompatible with strong oxidizing agents, strong bases.
Water Solubility <0.01 g/100 mL at 18 ºC

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CV5601000
CHEMICAL NAME :
Benzamide, p-nitro-
CAS REGISTRY NUMBER :
619-80-7
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C7-H6-N2-O3
MOLECULAR WEIGHT :
166.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
REFERENCE :
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0183-0462 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
476 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0183-0462
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 6,53,1954
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 28,335,1994

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Precautionary Statements P301 + P312 + P330
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes Xn:Harmful
Risk Phrases R22
Safety Phrases S27-S28-S36/37/39-S45
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS CV5601000
HS Code 2924299090

 Synthetic Route

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles2

More Articles
Observation of amide anions in solution by electrospray ionization mass spectrometry.

J. Am. Soc. Mass Spectrom. 11(12) , 1061-4, (2000)

Negative quasimolecular ions of aromatic carboxylic acid amides have been observed unexpectedly under electrospray ionization conditions. Hypothetically, deprotonation of either carboxamide or carboxi...

Preparation of nitriles from primary amides under Swern oxidation conditions. Nakajima N and Ubukata M.

Tetrahedron Lett. 38(12) , 2099-2102, (1997)

 Synonyms

4-Nitrobenzamide
Benzamide, 4-nitro-
EINECS 210-613-7
4-Nitrobenzolcarboxamid
4-Nitrophenylformamide
MFCD00007994
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