Tetrahedron letters

A two step synthesis of BzR/GABAergic active flavones via a Wacker-related oxidation

M Lorenz, MS Kabir, JM Cook

Index: Lorenz, Michael; Shahjahan Kabir; Cook, James M. Tetrahedron Letters, 2010 , vol. 51, # 7 p. 1095 - 1098

Full Text: HTML

Citation Number: 19

Abstract

... The initial idea for a two step process for the synthesis of various flavones originated from the work of Maldonado et al. who had employed a process they termed, a Wacker–Cook oxidation. ... Importantly, no byproduct was observed from the Michael addition to generate the dihydroflavone which is very difficult to convert to a flavone in some cases. ... 6c. References and notes. 1; (a) NJ-M. Raynal, L. Momparler, M. Charbonneau, RL Momparler; ...