The Mannich-type interaction of sulfur-containing CH acids with formaldehyde and primary amines

LI Vlasova, NZ Baibulatova, VA Dokichev…

Index: Vlasova; Baibulatova; Dokichev; Tomilov Russian Chemical Bulletin, 2012 , vol. 61, # 11 p. 2129 - 2132 Izv. Akad. Nauk, Ser. Khim., 2012 , # 11 p. 2112 - 2115,4

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Citation Number: 3

Abstract

Abstract One-pot reactions of dimethyl sulfonyldiacetate and N-methyl-2 r, 6 c-di (methoxycarbonyl)-3 t, 5 t-diphenyltetrahydro-1, 4-thiazine 1, 1-dioxide with formaldehyde and primary amines lead to derivatives of 9-thia-3, 7-diazabicyclo [3.3. 1] nonane 9, 9- dioxide resulted from decarboxylation of the ester groups at the positions 1 and 5. The effects of the reaction conditions and structure of the starting reagents on the yields of 9- ...