Synlett

H14 [NaP5W30O110] as an efficient catalyst for the one-pot synthesis of α-amino nitriles

…, MM Heravi, K Bakhtiari, V Zadsirjan, FF Bamoharram

Index: Oskooie, Hossein A.; Heravi, Majid M.; Bakhtiari, Khadijeh; Zadsirjan, Vahideh; Bamoharram, Fatemeh F. Synlett, 2006 , # 11 p. 1768 - 1770

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Citation Number: 20

Abstract

Abstract In this study, the synthesis of some α-amino nitriles is reported. The compounds were prepared by the nucleophilic addition reaction of aldehydes and amines with TMSCN in the presence of a catalytic amount of H 14 [NaP 5 W 30 O 110], Preyssler's heteropoly acid, in excellent yields. The catalyst can be recovered and reused in subsequent reactions.