Synthesis of. alpha.-keto esters via palladium-catalyzed double carbonylation

T Sakakura, H Yamashita, T Kobayashi…

Index: Sakakura, Toshiyasu; Yamashita, Hiroshi; Kobayashi, Toshi-aki; Hayashi, Teruyuki; Tanaka, Masato Journal of Organic Chemistry, 1987 , vol. 52, # 26 p. 5733 - 5740

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Citation Number: 53

Abstract

In recent years, increasing importance has been placed on the utilization of carbon monoxide for'organic synthesis.'Of particular industrial value are those reactions in which more than one unit of carbon monoxide are incorporated in the products. One reaction of considerable interest in this field is the direct reductive carbonylation of carbon monoxide with the chief aim being the synthesis of C2 oxygenates such as ethylene glycol, ethanol, ...