Biochemical and Biophysical Research Communications 2013-06-21

Epigenetic regulation of microRNA expression in renal cell carcinoma

Miriam Schiffgen, Doris H. Schmidt, Alexander von Rücker, Stefan C. Müller, Jörg Ellinger

Index: Biochem. Biophys. Res. Commun. 436(1) , 79-84, (2013)

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Abstract

• microRNAs are silenced by histone acetylation. • 5-Aza-2′dC and SAHA induce microRNA re-expression. • 5-Aza-2′dC and SAHA are most efficient in combination.