Journal of Chromatography A 2015-05-22

Towards a full integration of optimization and validation phases: An analytical-quality-by-design approach

C. Hubert, S. Houari, E. Rozet, P. Lebrun, Ph. Hubert

Index: J. Chromatogr. A. 1395 , 88-98, (2015)

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Abstract

• An enhanced quality-by-design strategy throughout the analytical method lifecycle. • Quantitative design space: an innovative approach for development of analytical methods. • Integrated approaches for optimization and validation phases. • Full validation of an operational space.