Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] / Ministerstvo meditsinskoi i mikrobiologicheskoi promyshlennosti SSSR 1996-02-01

[A laboratory method for sensitized isomerization of polyene macrolides].

Iu D Shenin, A I Filippova

Index: Antibiot. Khimioter. 41(2) , 16-21, (1996)

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Abstract

The study was aimed at the development of a laboratory procedure for isomerization of polyene macrolides in the presence of sensitizers. The reaction was performed with exposure of levorin solutions to the xenon lamp irradiation in the presence of rose bengal B as a sensitizers. It was shown that levoristatin contain in the levorin sample was not degraded under the experimental conditions. The use of a redetermined variant of the Vierordt's methods made it possible to offer a design formula for the estimation of the isolevorin content in solutions in the presence of levorin.