Rose Bengal sodium

Modify Date: 2024-01-02 10:51:15

Rose Bengal sodium structure	Common Name	Rose Bengal sodium
	CAS Number	632-69-9	Molecular Weight	1017.636
	Density	N/A	Boiling Point	757.8ºC at 760 mmHg
	Molecular Formula	C₂₀H₂Cl₄I₄Na₂O₅	Melting Point	>300°C
	MSDS	Chinese USA	Flash Point	412.1ºC

Use of Rose Bengal sodium

Rose Bengal sodium is a crimson-coloured dye, and it is a synthetic fluorescein derivative with the principal component being 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. Rose Bengal sodium has been widely used as an ophthalmic diagnostic agents, it can detect desiccated or damaged cells on the ocular surface. Rose Bengal sodium exhibits antiviral activities[1][2].

Name	Acid Red 94
Synonym	More Synonyms

Description	Rose Bengal sodium is a crimson-coloured dye, and it is a synthetic fluorescein derivative with the principal component being 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. Rose Bengal sodium has been widely used as an ophthalmic diagnostic agents, it can detect desiccated or damaged cells on the ocular surface. Rose Bengal sodium exhibits antiviral activities[1][2].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Others
References	[1]. Doughty MJ, et, al. Fluorescence characteristics of sodium fluorescein-rose bengal ophthalmic solution mixtures. Cont Lens Anterior Eye. 2014 Oct; 37(5): 358-62. [2]. Roat MI, et, al. The antiviral effects of rose bengal and fluorescein. Arch Ophthalmol. 1987 Oct; 105(10): 1415-7.

Description

Related Catalog

Signaling Pathways >> Anti-infection >> Influenza Virus

Research Areas >> Others

References

[1]. Doughty MJ, et, al. Fluorescence characteristics of sodium fluorescein-rose bengal ophthalmic solution mixtures. Cont Lens Anterior Eye. 2014 Oct; 37(5): 358-62.

[2]. Roat MI, et, al. The antiviral effects of rose bengal and fluorescein. Arch Ophthalmol. 1987 Oct; 105(10): 1415-7.

Boiling Point	757.8ºC at 760 mmHg
Melting Point	>300°C
Molecular Formula	C₂₀H₂Cl₄I₄Na₂O₅
Molecular Weight	1017.636
Flash Point	412.1ºC
Exact Mass	1015.463013
PSA	93.40000
LogP	8.10410
Water Solubility	soluble

Rose Bengal sodium MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LM5920000

CHEMICAL NAME :: Fluorescein, 4,5,6,7-tetrachloro-2',4',5',7'-tetraiodo-, disodium salt

CAS REGISTRY NUMBER :: 632-69-9

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C20-H2-Cl4-I4-O5.2Na

MOLECULAR WEIGHT :: 1017.60

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 707 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Endocrine - thyroid tumors

REFERENCE :: JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 77,277,1986 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 650 mg/kg

SEX/DURATION :: female 8-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 24,391,1982

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 400 mg/kg

SEX/DURATION :: female 8-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 24,391,1982

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 20 gm/kg

SEX/DURATION :: female 8-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4)

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 24,391,1982

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi:Irritant;
Risk Phrases	R36
Safety Phrases	S22-S24/25-S37/39-S26
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	LM5920000

ROSE BENGAL LACTONE

CAS#:4159-77-7

Rose Bengal sodium

CAS#:632-69-9

Literature: Tetrahedron, , vol. 41, # 11 p. 2183 - 2190

Spiro[isobenzof...

CAS#:24545-87-7

Rose Bengal sodium

CAS#:632-69-9

Literature: Journal of Physical Chemistry, , vol. 87, # 25 p. 5248 - 5251

Precursor 2
CAS#:4159-77-7 ROSE BENGAL LACTONE CAS#:24545-87-7 Spiro[isobenzof...
DownStream 2
CAS#:4159-77-7 ROSE BENGAL LACTONE CAS#:61738-01-0 Rose Bengal dia...

Rescue of cortical neurovascular functions during the hyperacute phase of ischemia by peripheral sensory stimulation.

Neurobiol. Dis. 75 , 53-63, (2015)

To investigate the potential therapeutic effects of peripheral sensory stimulation during the hyperacute phase of stroke, the present study utilized electrophysiology and photoacoustic imaging techniq...

The promoting effects of food dyes, erythrosine (Red 3) and rose bengal B (Red 105), on thyroid tumors in partially thyroidectomized N-bis(2-hydroxypropyl)-nitrosamine-treated rats.

Jpn. J. Cancer Res. 79(3) , 314-9, (1988)

The effects of erythrosine (Red 3), rose bengal B (Red 105) and thyroidectomy on the development of thyroid tumor were examined in male Wistar rats treated with N-bis(2-hydroxypropyl)nitrosamine (DHPN...

[A laboratory method for sensitized isomerization of polyene macrolides].

Antibiot. Khimioter. 41(2) , 16-21, (1996)

The study was aimed at the development of a laboratory procedure for isomerization of polyene macrolides in the presence of sensitizers. The reaction was performed with exposure of levorin solutions t...

MFCD00151169

Food Red No. 105

LTE4 ELISA

r105sodium

benzoic acid, 2,3,4,5-tetrachloro-6-(6-hydroxy-2,4,5,7-tetraiodo-3-oxo-3H-xanthen-9-yl)-, disodium salt

disodium (3-oxo-6-oxido-2,4,5,7-tetraiodo-3H-xanthen-9-yl)-3,4,5,6-tetrachlorobenzoate

Benzoic acid, 2,3,4,5-tetrachloro-6-(6-hydroxy-2,4,5,7-tetraiodo-3-oxo-3H-xanthen-9-yl)-, sodium salt (1:2)

LTD4 ELISA

Bengal Rose

MDC ELISA

UNII:956575SN5L

LTB4 ELISA

Disodium 2,3,4,5-tetrachloro-6-(2,4,5,7-tetraiodo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate

LTC4 ELISA

CI Acid red 94

Rose Bengal Sodium Salt

Red no. 105

EINECS 211-182-8

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Rose Bengal sodium
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Rose Bengal sodium
Price: ￥595.0/5g ￥165.0/1g
Purity: 95.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Rose Bengal sodium
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Acid red 94
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Acid Red 94
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Get all suppliers and price by the below link:

Rose Bengal sodium suppliers

Rose Bengal sodium price

Rose Bengal sodium

Use of Rose Bengal sodium

Names