Molecules 2013-01-01

A new hydroxychavicol dimer from the roots of Piper betle.

Chwan-Fwu Lin, Tsong-Long Hwang, Chun-Chien Chien, Huei-Yu Tu, Horng-Liang Lay

Index: Molecules 18(3) , 2563-70, (2013)

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Abstract

A new hydroxychavicol dimer, 2-(g'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.