ortho-Substituted unsymmetrical biaryls from aryl tert-butyl sulfones

J Clayden, M Julia

Index: Clayden, Jonathan; Julia, Marc Journal of the Chemical Society, Chemical Communications, 1993 , # 22 p. 1682 - 1683

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Citation Number: 12

Abstract

The tert-butylsulfonyl group has been shown to be an excellent director of ortholithiation, making ortho-substituted aryl tert-butyl sulfones very readily available.' The use of such molecules to the synthetic chemist would be enhanced if the sulfonyl group could subsequently be transformed into another substituent. In this communication, we describe the substitution of the aryl tert-butylsulfonyl group by aryl- magnesium halides under nickel catalysis to give ortho- substituted ...