Journal of Photochemistry and Photobiology B: Biology 2012-08-01

Investigations on the binding of human hemoglobin with orange I and orange II

Yan-Qing Wang, Hong-Mei Zhang, Yan-Qing Wang, Hong-Mei Zhang

Index: J. Photochem. Photobiol. B, Biol. 113 , 14-21, (2012)

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Abstract

Highlights ► The interactions of orange I and orange II with Hb were studied. ► The multi-intermolecular forces played major roles in stabilizing dye–Hb complexes. ► There is a single class of binding site in human hemoglobin. ► There is a small loss of α-helical secondary structure of Hb induced by dye.