CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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DB7084000
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CHEMICAL NAME :
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Benzenesulfonic acid, 4-((2-hydroxy-1-naphthalenyl)azo)-, monosodium salt
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CAS REGISTRY NUMBER :
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633-96-5
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LAST UPDATED :
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199710
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DATA ITEMS CITED :
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10
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MOLECULAR FORMULA :
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C16-H12-N2-O4-S.Na
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MOLECULAR WEIGHT :
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351.35
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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150 gm/kg/43W-C
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TOXIC EFFECTS :
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Liver - other changes Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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240 mg/kg/3D-I
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TOXIC EFFECTS :
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Liver - other changes Biochemical - Metabolism (Intermediary) - lipids including transport
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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150 gm/kg
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SEX/DURATION :
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male 43 week(s) pre-mating
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TOXIC EFFECTS :
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Reproductive - Paternal Effects - testes, epididymis, sperm duct
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intratesticular
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DOSE :
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10 mg/kg
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SEX/DURATION :
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male 1 day(s) pre-mating
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TOXIC EFFECTS :
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Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct
MUTATION DATA
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TYPE OF TEST :
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Mutation in mammalian somatic cells
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TEST SYSTEM :
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Human Lymphocyte
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DOSE/DURATION :
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12 nmol/L
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REFERENCE :
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MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 249,265,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1433 No. of Facilities: 4422 (estimated) No. of Industries: 42 No. of Occupations: 44 No. of Employees: 43457 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1433 No. of Facilities: 3061 (estimated) No. of Industries: 22 No. of Occupations: 31 No. of Employees: 38768 (estimated) No. of Female Employees: 14382 (estimated)
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