Journal of Chromatography A 2014-10-01

A novel urea-functionalized surface-confined octadecylimidazolium ionic liquid silica stationary phase for reversed-phase liquid chromatography.

Mingliang Zhang, Ting Tan, Zhan Li, Tongnian Gu, Jia Chen, Hongdeng Qiu

Index: J. Chromatogr. A. 1365 , 148-55, (2014)

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Abstract

One-pot synthesis of surface-confined ionic liquid functionalized silica spheres was proposed using N-(3-aminopropyl)imidazole, _-isopropyltriethoxysilane and 1-bromooctadecane as starting materials. The surface modification of the silica spheres was successful with a high surface density of octadecylimidazolium, enabling the utilization of this new urea-functionalized ionic liquid-grafted silica material as stationary phase for high-performance liquid chromatography in reversed-phase mode. The long aliphatic chain combined with the multiple polar group embedded in the ligands imparted the new stationary phase fine selectivity towards PAH isomers and polar aromatics and higher affinity for phenolic compounds. The unique features of the new material, especially the effect of the urea group on the retention were elucidated by mathematic modeling.