Journal of chromatography. A 2010-10-22

Simultaneous determination of UV filters and polycyclic musks in aqueous samples by solid-phase microextraction and gas chromatography-mass spectrometry.

Hongtao Liu, Ling Liu, Yiquan Xiong, Xuemei Yang, Tiangang Luan

Index: J. Chromatogr. A. 1217(43) , 6747-53, (2010)

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Abstract

A simple, precise and accurate method for the simultaneous determination of four UV filters and five polycyclic musks (PCMs) in aqueous samples was developed by solid-phase microextraction coupled with gas chromatography-mass spectrometry (SPME-GC-MS). The operating conditions affecting the performance of SPME-GC-MS, including fiber thickness, desorption time, pH, salinity, extraction time and temperature have been carefully studied. Under optimum conditions (30 μm PDMS fiber, 7 min desorption time, pH 7, 10% NaCl, 90 min extraction time at 24°C), the correlation coefficients (r(2)) of the calibration curves of target compounds ranged from 0.9993 to 0.9999. The limit of detection (LOD) and limit of quantification (LOQ) ranged from 0.2 to 9.6 ng L⁻¹ and 0.7 to 32.0 ng L⁻¹, respectively. The developed procedure was applied to the determinations of four UV filters and five PCMs in river water samples and internal standard was used for calibration to compensate the matrix effect. Good relative recoveries were obtained for spiked river water at low, medium and high levels. The proposed SPME method was compared with traditional SPE procedure and the results found in river water using both methods were in the same order of magnitude and both are quite agreeable.Copyright © 2010 Elsevier B.V. All rights reserved.