Chemical Communications 2005-06-14

A new mechanism for nucleophilic substitution at a thiophosphoryl centre revealed by the reaction of diisopropylamine with PSCl3.

Martin J P Harger

Index: Chem. Commun. (Camb.) (22) , 2863-5, (2005)

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Abstract

The reaction of PSCl3 with Pr(i)2NH at 60 degrees C affords the disubstitution product (Pr(i)2N)2P(S)Cl without first forming the monosubstitution product Pr(i)2NP(S)Cl2; a P(III) compound (possibly PCl3) generated in situ seems to be a crucial intermediate.