Bioscience, Biotechnology, and Biochemistry 2009-11-01

Short-step synthesis of a resveratrol derivative from commercially available 1,3-dimethoxybenzene and 4-vinylanisole.

Takashi Iijima, Hidefumi Makabe

Index: Biosci. Biotechnol. Biochem. 73(11) , 2547-8, (2009)

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Abstract

An efficient synthesis of tri-O-methylated resveratrol is presented using an advanced Heck reaction promoted by Pd(dba)(2) in the presence of P(t-Bu)(3).