Journal of Natural Products 2011-10-28

Lanostane and hopane triterpenes from the entomopathogenic fungus Hypocrella sp. BCC 14524.

Masahiko Isaka, Panida Chinthanom, Malipan Sappan, Rungtiwa Chanthaket, J Jennifer Luangsa-ard, Samran Prabpai, Palangpon Kongsaeree

Index: J. Nat. Prod. 74 , 2143-50, (2011)

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Abstract

Seven new lanostane-type triterpenes, hypocrellols A-G (1-7), and six new hopane-type triterpenes, 7β,15α-dihydroxy-22(29)-hopene (8), 3β,7β-dihydroxy-22(29)-hopene (9), 3β-acetoxy-15α-hydroxy-22(29)-hopene (10), 3β,7β,15α,22-tetrahydroxyhopane (11), 3β-acetoxy-7β,15α,22-trihydroxyhopane (12), and 7β,15α,22-trihydroxyhopane (13), were isolated from the scale insect pathogenic fungus Hypocrella sp. BCC 14524. The structures of the new compounds were elucidated by analyses of the NMR spectroscopic and mass spectrometry data. The structure of 1 was confirmed by X-ray crystallography.