Organic letters

Synthesis of 3-substituted indazoles from arynes and N-tosylhydrazones

P Li, J Zhao, C Wu, RC Larock, F Shi

Index: Li, Pan; Zhao, Jingjing; Wu, Chunrui; Larock, Richard C.; Shi, Feng Organic Letters, 2011 , vol. 13, # 13 p. 3340 - 3343

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Citation Number: 60

Abstract

Readily available, stable, and inexpensive N-tosylhydrazones react with arynes under mild reaction conditions to afford 3-substituted indazoles in moderate to good yields. The reaction appears to involve a dipolar cycloaddition of in situ generated diazo compounds and arynes.