Tetrahedron

Gallium dichloride-mediated reductive Friedel-Crafts reaction

Y Hashimoto, K Hirata, H Kagoshima, N Kihara…

Index: Hashimoto, Yukihiko; Hirata, Kazujuki; Kagoshima, Hirotaka; Kihara, Nobuhiro; Hasegawa, Masaki; Saigo, Kazuhiko Tetrahedron, 1993 , vol. 49, # 27 p. 5969 - 5978

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Citation Number: 33

Abstract

In the presence of gallium dichloride, the reaction of carbonyl compounds or their dimethylacetals with aromatic compounds afforded Friedel-Crafts alkylated adducts in good yields. It was suggested that the adducts were obtained by way of a reduction of the carbonyl compounds or their dimethylacetals, followed by the Friedel-Crafts reaction in one-pot. This is the first organic synthetic method with gallium dichloride, low valent gallium.