Journal of the American Chemical Society

Asymmetric synthesis of monosubstituted and. alpha.,. alpha.-disubstituted. alpha.-amino acids via diastereoselective glycine enolate alkylations

RM Williams, MN Im

Index: Journal of the American Chemical Society, , vol. 113, # 24 p. 9276 - 9286

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Citation Number: 241

Abstract

... Acknowledgment. The research was partially funded by a joint US/Japan Award 8613516. ... catalog no. 33,187-2. 0 1991 American Chemical Society Page 2. ... For the unactivated alkyl halides, addition of HMPA (THF/HMPA, 1O:l) significantly improves the chemical yields. ...