Tetrahedron

Alkylations en absence de solvant organique—3: Preparation d'ethers aliphatiques par alkylation des alcoolates dans des conditions douces et economiques

…, G Bram, G Decodts, A Loupy, P Pigeon, J Sansoulet

Index: Barry, J.; Bram, G.; Decodts, G.; Loupy, A.; Pigeon, P; Sansoulet, J. Tetrahedron, 1984 , vol. 40, # 15 p. 2945 - 2950

Full Text: HTML

Citation Number: 27

Abstract

n-Octyl ethers are obtained by reacting n-octyl halides with preformed alkoxides, or better, prepared in situ from ROH and solid KOH. Reactions are performed without any solvent but in the presence of a catalytic amount of tetra-alkyl ammonium salt (Aliquat 336). Good yields (⩾ 92% for primary R) are obtained at moderate temperatures and with easy work-up; for t- C4H9O-, elimination is a side reaction, and the effects of temperature and of the nature of ...