Biulleten' eksperimental'noi biologii i meditsiny 1990-01-01

[Ultrastructural features of heart insufficiency and its correction during the post-asphyxia period].

P N Eskunov, S S Stepanov, V V Semchenko

Index: Biull. Eksp. Biol. Med. 109(1) , 72-4, (1990)

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Abstract

The ultrastructure of myocardium was studied in the experiments on rats during 24 hours after 6-min mechanical asphyxia with following clinical death. It has been established that the contractile cardiac apparatus of myocytes lesions on the intracellular edema background is the main while energy production process impairs insignificantly. The effectiveness of anti-hypoxia, membrane stability and protease inhibiting preparations for prevention of postresuscitation myocardium lesion was examined. The contrykal protective action, suppressing the proteolytic ferment hyperactivity was determined.