Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Trifluoroacetamide was reacted with diacids in the presence of N-ethyl-N-dimethyl-aminopropylcarbodiimide and of 1-hydroxybenzotriazole to afford cyclic imides of different ring size, providing a single step asymmetric synthesis of thalidomide. ... A one-step general synthesis of cyclic imides.