Organic Letters 2000-11-16

Total synthesis of (+)-7-deoxypancratistatin from furan.

J L Aceña, O Arjona, M L León, J Plumet

Index: Org. Lett. 2(23) , 3683-6, (2000)

Full Text: HTML

Abstract

A new total synthesis of (+)-7-deoxypancratistatin 1 has been accomplished in 19 steps (8% overall yield) from two readly available compounds, furan and trans-1,2-bis(phenylsulfonyl)ethylene.

Structure	Name/CAS No.	Molecular Formula	Articles
	Benzene,1,1'-[(1E)-1,2-ethenediylbis(sulfonyl)]bis- CAS:963-16-6	C₁₄H₁₂O₄S₂

O. De Lucchi, L. Pasquato
[Tetrahedron 44 , 6755, (1988)]

O. De Lucchi et al.
[J. Org. Chem. 49 , 596, (1984)]

L.A. Paquette et al.
[Tetrahedron 42 , 1789, (1986)]

A. Azzena et al.
[Synth. Commun. 18 , 351, (1988)]

Binap-gold (I) trifluoroacetate as a bifunctional catalyst f...
[Tetrahedron Asymmetry 21(9) , 1184-86, (2010)]

Total synthesis of (+)-7-deoxypancratistatin from furan.

Abstract

Related Compounds