Advanced Synthesis & Catalysis

Copper (II)??Catalyzed Reactions of Dimethylformamide with Phenylacetonitrile and Sulfur to Form N, N??Dimethylthioamides

Y Qu, Z Li, H Xiang, X Zhou

Index: Qu, Yanyang; Li, Zhengkai; Xiang, Haifeng; Zhou, Xiangge Advanced Synthesis and Catalysis, 2013 , vol. 355, # 16 p. 3141 - 3146

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Citation Number: 8

Abstract

Abstract: Novel copper-catalyzed three-component reactions of phenylacetonitrile, sulfur and DMF (dimethyformamide) for the selective preparation of N, N-dimethylthiobenzamide and N, N-dimethyl-2-phenylethanethioamides in yields of up to 96% are described. Keywords: catalysis; copper; multi-component reactions; sulfur; thioamides