Journal of Antibiotics 1983-12-01

Novel antitumor agents CI-920, PD 113,270 and PD 113,271. II. Isolation and characterization.

S S Stampwala, R H Bunge, T R Hurley, N E Willmer, A J Brankiewicz, C E Steinman, T A Smitka, J C French

Index: J. Antibiot. 36 , 160-1605, (1983)

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Abstract

A complex of structurally related compounds that exhibit in vivo antileukemic activity was isolated from fermentation broths of a new streptomycete. The components of this complex are water soluble phosphate esters containing a conjugated triene system. The isolation and characterization of three of these components are described.