Tetrahedron letters

NaIO 4-mediated C–H activation of alkylbenzenes and alkanes with LiBr

TM Shaikh, A Sudalai

Index: Shaikh, Tanveer M.; Sudalai, Arumugam Tetrahedron Letters, 2005 , vol. 46, # 33 p. 5589 - 5592

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Citation Number: 25

Abstract

NaIO4 oxidizes lithium bromide efficiently under acidic conditions to functionalize alkylbenzenes and alkanes and produce the corresponding bromo and acetoxy derivatives in excellent yields. The protocol also demonstrates the direct conversion of cyclohexane into trans-1, 2-dibromocyclohexane in moderate yield.