Pharmacological Research 1989-01-01

Effect of fipexide on passive avoidance behaviour in rats.

G Serra, M Collu, M C Martellotta, A Forgione, W Fratta

Index: Pharmacol. Res. 21(5) , 603-8, (1989)

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Abstract

The effect of fipexide, administered at different intervals after the learning trial of a single step-through type passive avoidance situation was studied. The administration of fipexide immediately after the learning trial resulted in a long-lasting facilitation of passive avoidance behaviour. On the contrary, the administration of this compound 1 h prior to the retention test failed to influence passive avoidance behaviour. The results suggest that fipexide facilitates memory consolidation but does not influence retrieval processes.