Combinatorial Chemistry & High Throughput Screening 2013-09-01

Multicomponent reactions for the synthesis of functionalized imidazoles.

Samereh Seyfi, Zinatossadat Hossaini, Faramarz Rostami-Charati

Index: Comb. Chem. High Throughput Screen 16(8) , 652-6, (2013)

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Abstract

An efficient synthesis of functionalized tetrahydroimidazoles via a one-pot tandem reaction between ninhydrin, primary alkylamines, arylisocyanates or arylisothiocyanates, acetylenic esters and triphenylphosphine is described.