Ninhydrin

Modify Date: 2024-01-01 20:43:10

Ninhydrin structure	Common Name	Ninhydrin
	CAS Number	485-47-2	Molecular Weight	178.141
	Density	1.7±0.1 g/cm3	Boiling Point	449.3±45.0 °C at 760 mmHg
	Molecular Formula	C₉H₆O₄	Melting Point	250 °C (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	239.7±25.2 °C
	Symbol	GHS07	Signal Word	Warning

Use of Ninhydrin

Ninhydrin can be used as a chromogenic analytical probe for the quantification of amino acids and proteins.

Name	ninhydrin
Synonym	More Synonyms

Description	Ninhydrin can be used as a chromogenic analytical probe for the quantification of amino acids and proteins.
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	IC50: chromogenic analytical probe[1]
In Vitro	Ninhydrin is used in amino acid analysis of proteins. Except proline, Most amino acids can be hydrolyzed and react with ninhydrin. The amino acids are then quantified colorimetrically after separation by chromatography. Ninhydrin reacts with primary and secondary amines producing a blue or purple reaction product: diketohydrindylidene-diketohydrindamine.
References	[1]. Omar MA, et al. Utility of ninhydrin reagent for spectrofluorimetric determination of heptaminol in human plasma.Luminescence. 2018 Sep;33(6):1107-1112. [2]. Anantharaman S, et al. Ninhydrin-sodium molybdate chromogenic analytical probe for the assay of amino acids and proteins.rSpectrochim Acta A Mol Biomol Spectrosc. 2017 Feb 15;173:897-903.

Density	1.7±0.1 g/cm3
Boiling Point	449.3±45.0 °C at 760 mmHg
Melting Point	250 °C (dec.)(lit.)
Molecular Formula	C₉H₆O₄
Molecular Weight	178.141
Flash Point	239.7±25.2 °C
Exact Mass	178.026611
PSA	74.60000
LogP	1.07
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.737
Storage condition	Store at RT.
Stability	Stable. Incompatible with amines, alkalies, strong bases. Light-sensitive.
Water Solubility	0.1-0.5 g/100 mL at 20 ºC

Ninhydrin MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NK5425000

CHEMICAL NAME :: 1,3-Indandione, 2,2-dihydroxy-

CAS REGISTRY NUMBER :: 485-47-2

BEILSTEIN REFERENCE NO. :: 1910963

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C9-H6-O4

MOLECULAR WEIGHT :: 178.15

WISWESSER LINE NOTATION :: L56 BV DV CHJ CQ CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,28,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 78 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Vascular - regional or general arteriolar or venous dilation Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 151,719,1957 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1175 No. of Facilities: 33 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 594 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1175 No. of Facilities: 476 (estimated) No. of Industries: 4 No. of Occupations: 9 No. of Employees: 5565 (estimated) No. of Female Employees: 4002 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful
Risk Phrases	R22;R36/37/38
Safety Phrases	S26-S28A-S45-S16
RIDADR	UN 1170 3/PG 2
WGK Germany	3
RTECS	NK5425000
Hazard Class	3.0
HS Code	2915900090

Precursor 10
CAS#:606-23-5 1,3-INDANDIONE CAS#:501-53-1 Benzyl chloroformate CAS#:1283-97-2 phenyliodonium ... CAS#:20847-51-2 2,2-diethoxyind...
CAS#:65299-21-0 2,2-dimethoxy-1... CAS#:1260-17-9 CARMINIC ACID CAS#:121-33-5 Vanillin CAS#:90271-93-5 3-Bromo-1H-inde...
CAS#:96042-30-7 2-[2-[(E)-2-[4-... CAS#:83-33-0 1-Indanone
DownStream 8
CAS#:112359-95-2 N-[2-(hydroxyam... CAS#:4122-57-0 3-methoxy-3H-is... CAS#:5103-42-4 Hydrindantin CAS#:412008-97-0 azine-bisindandione
CAS#:1801-25-8 3-benzhydrylide... CAS#:1807-49-4 1,3-Indandione,... CAS#:10323-20-3 D-Arabinose CAS#:141-82-2 Malonic acid

HS Code	2915900090
Summary	2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

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2,2-Dihydroxy-1H-indene-1,3(2H)-dione

Triketohydrinden Hydrate

Ninhydrin

2,2-Dihydroxy-1,3-indanedione

Ninhydrin,spectrophotometric grade

MFCD00003791

Ninhydrin Spray

Ningidrin

indane-1,2,3-trione monohydrate

NyNhydriN

NinhydrinGr

1,2,3-Indanetrione monohydrate

Trioxohydrindene monohydrate

Ninhydrin,ozone friendly ready to use spray

1H-Indene-1,2,3-trione hydrate

Ninhydrin (contains Acetic Acid) Ethanol

1,2,3-Indantrione, 2-hydrate

EINECS 207-618-1

NINHYDRINE

1,2,3-triketohydrindene hydrate

1H-Indene-1,3(2H)-dione, 2,2-dihydroxy-

2,2-dihydroxy-2H-indene-1,3-dione

Ninhydrin hydrate

NinhydrinA.R.

NIN

Ninthydrin

1,3-Indandione, 2,2-dihydroxy-

1,2,3-Indantrione monohydrate

1,2,3-Indantrione monohydrate,2,2-Dihydroxy-1,3-indanedione,Trioxohydrindene monohydrate

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Ninhydrin
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Ninhydrin
Price: ￥98.0/5g ￥288.0/25g
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Ninhydrin
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: ninhydrin
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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