A New Approach to the Synthesis of N, N??Dialkyladenine Derivatives

…, S Carvalho, AM Dias, FH Fernandes…

Index: Alves, M. Jose; Carvalho, M. Alice; Carvalho, Silvia; Dias, Alice M.; Fernandes, Francisco H.; Proenca, M. Fernanda European Journal of Organic Chemistry, 2007 , # 29 p. 4881 - 4887

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Citation Number: 7

Abstract

Abstract N, N-Dialkyladenine derivatives were prepared by two different reaction sequences starting from 5-amino-4-cyanoformimidoylimidazoles. When these imidazoles were treated with dimethylformamide diethyl acetal, a 5-aminomethyleneamino-4- cyanoformimidoylimidazole was isolated and evolved to the N, N-dialkyladenine in the presence of a secondary alkylamine. The same purine structure was isolated when the 5- ...