e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Mild regioselective halogenation of activated pyridines with N-bromosuccinimide

V Cañibano, JF Rodriguez, M Santos…

Index: Synthesis, , # 14 p. 2175 - 2179

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Citation Number: 54

Abstract

... Synthesis 2001(14): 2175-2179 DOI: 10.1055/s-2001-18070. PAPER. © Georg Thieme Verlag Stuttgart · New York Mild Regioselective Halogenation of Activated Pyridines with N-Bromosuccinimide. Victoria Cañibano a , Justo ...

Pyridin-3-ol Structure

~33%

2,6-Dibromo-3-pyridinol Structure

2,6-Dibromo-3-p...

2,4,6-TRIBROMO-3-PYRIDINOL Structure

2,4,6-TRIBROMO-...

Pyridin-3-ol Structure

~31%

2-Brompyridin-3-ol Structure

2-Brompyridin-3-ol

2,6-Dibromo-3-pyridinol Structure

2,6-Dibromo-3-p...

2,4,6-TRIBROMO-3-PYRIDINOL Structure

2,4,6-TRIBROMO-...

3-Aminopyridine Structure

3-Aminopyridine

~6%

5-Amino-2-bromopyridine Structure

5-Amino-2-bromo...

2-Bromo-3-pyridinamine Structure

2-Bromo-3-pyrid...

2,6-Dibromo-3-pyridinamine Structure

2,6-Dibromo-3-p...

Pyridin-3-ol Structure

~33%

2,6-Dibromo-3-pyridinol Structure

2,6-Dibromo-3-p...

2,4,6-TRIBROMO-3-PYRIDINOL Structure

2,4,6-TRIBROMO-...

Pyridin-3-ol Structure

~4%

2-Brompyridin-3-ol Structure

2-Brompyridin-3-ol

2,6-Dibromo-3-pyridinol Structure

2,6-Dibromo-3-p...

2,4,6-TRIBROMO-3-PYRIDINOL Structure

2,4,6-TRIBROMO-...

4-AMINOPYRIDINE Structure

4-AMINOPYRIDINE

~10%

3-Bromo-4-pyridinamine Structure

3-Bromo-4-pyrid...

3,5-Dibromo-4-pyridinamine Structure

3,5-Dibromo-4-p...

4-Hydroxypyridine Structure

4-Hydroxypyridine

~32%

3-Bromo-4-pyridinol Structure

3-Bromo-4-pyridinol

3,5-dibromo-4-pyridinol Structure

3,5-dibromo-4-p...

4-AMINOPYRIDINE Structure

4-AMINOPYRIDINE

~65%

3-Bromo-4-pyridinamine Structure

3-Bromo-4-pyrid...

3,5-Dibromo-4-pyridinamine Structure

3,5-Dibromo-4-p...