Copper??Catalyzed Domino Reaction Involving C–C Bond Cleavage To Construct 2??Aryl Quinazolinones

LX Wang, JF Xiang, YL Tang

Index: Wang, Li-Xia; Xiang, Jun-Feng; Tang, Ya-Lin European Journal of Organic Chemistry, 2014 , vol. 2014, # 13 p. 2682 - 2685

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Citation Number: 17

Abstract

Abstract A copper-catalyzed approach for the synthesis of 2-aryl-quinazolinones through a domino reaction involving C–C bond cleavage is described. This protocol involves intramolecular C–C bond cleavage to construct 2-aryl-quinazolinones, which may offer an alternative method to prepare medically important quinazolinone derivatives and a new strategy for C–C bond cleavage. Besides C–C bond cleavage, this domino reaction ...