Bioorganic & Medicinal Chemistry 2009-01-01

Antimalarial acridines: Synthesis, in vitro activity againstP. falciparumand interaction with hematin

Lucie Guetzoyan, Xiao-Min Yu, Florence Ramiandrasoa, Stéphanie Pethe, Christophe Rogier, Bruno Pradines, Thierry Cresteil, Martine Perrée-Fauvet, Jean-Pierre Mahy, Lucie Guetzoyan, Xiao-Min Yu, Florence Ramiandrasoa, Stéphanie Pethe, Christophe Rogier, Bruno Pradines, Thierry Cresteil, Martine Perrée-Fauvet, Jean-Pierre Mahy

Index: Bioorg. Med. Chem. 17(23) , 8032-9, (2009)

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Abstract

Synthesis of new 9-aminoacridines and evaluation of in vitro anti-malarial activity. Inhibitory effect on haem crystallization.