PANORAMA DU M�DECIN 2009-06-01

[Drug treatment for hypertrophic cardiomyopathy].

Pierre Gibelin

Index: Presse Med. 38(6) , 1001-4, (2009)

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Abstract

Drug treatment of hypertrophic cardiomyopathy is the first-line treatment, at the onset of clinical signs and symptoms. Beta-blockers are proposed for symptomatic patients with no gradient or with a gradient that appears only on exertion. Verapamil is the standard second-line drug,when the beta-blockers are insufficient or ineffective but must be avoided when there is blockage at rest with severe symptoms. Disopyramide is indicated for patients with obstruction who do not respond to beta blockers and/or verapamil. Treatment with anticoagulants is widely prescribed because this disease is highly emboligenic.