Highly regioselective, sequential, and multiple palladium-catalyzed arylations of vinyl ethers carrying a coordinating auxiliary: an example of a Heck triarylation …

P Nilsson, M Larhed, A Hallberg

Index: Nilsson; Larhed; Hallberg Journal of the American Chemical Society, 2001 , vol. 123, # 34 p. 8217 - 8225

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Citation Number: 131

Abstract

This article describes the development of new auxiliary-accelerated Heck multiarylations by intramolecular presentation of the oxidative addition complex. The introduction of a specific, palladium-coordinating dimethylamino group allows for the desired chelation-accelerated and chelation-controlled tri-and diarylation reactions. We report (a) the first example of a Heck triarylation process,(b) highly selective palladium-catalyzed diarylations of alkyl vinyl ...

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