Xenobiotica 1992-11-01

Mercapturic acid formation from 2-aminopyrazine in rats.

W H Lunn, J K Shadle

Index: Xenobiotica 22(11) , 1239-41, (1992)

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Abstract

1. The compound 2-aminopyrazine was given by oral gavage to normal rats and their urine collected. 2. A mercapturic acid containing the 2-aminopyrazine moiety was isolated from this urine. This represents the first example of this type of a metabolite from a pyrazine.