On??Column Solvent??Free Oxidative Cleavage Reactions of Vicinal Diols by Silica Gel and Paraperiodic Acid: Application to In??Situ Sequential Oxidation and …

SC Dakdouki, D Villemin, N Bar

Index: Dakdouki, Saada C.; Villemin, Didier; Bar, Nathalie European Journal of Organic Chemistry, 2012 , # 4 p. 780 - 784

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Abstract

Abstract An on-column solvent-free oxidative cleavage reaction of vicinal diols by paraperiodic acid supported on silica gel at room temperature is described. The resulting pure carbonyl compounds are prepared in good to excellent yields with short reaction times. The cleavage reactions proceed under mild conditions, which avoids further cyclization reactions of the product dialdehydes. This method is also used for sequential oxidation ...