Synthesis, 3D??QSAR, and Structural Modeling of Benzolactam Derivatives with Binding Affinity for the D2 and D3 Receptors

L López, J Selent, R Ortega, CF Masaguer…

Index: ChemMedChem, , vol. 5, # 8 p. 1300 - 1317

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Citation Number: 19

Abstract

... ChemMedChem, 5: 1300–1317. ... Volume: Issue: Page: ... distance of two groups of hydrogen bond donor (HBD) hotspots, one near the benzolactam carbonyl and the other in front of the pyridyl or pyrimidyl moiety present in fragment I of some compounds (eg, 5 c and 5 d; Figure 4 ...

~9%

~85%

~75%

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